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IVF cost in Iran

:·IVF cost in Iran

Due to the latest Iran’scurrency devaluation, now high quality medical services are available at muchaffordable prices. Iran has a good ranking in the world in total medicalscience especially in infertility treatments. The success rate of IVF in Iran ishigher than world average. The average IVF cost in Iran is as affordable as1,800-2,500$ for one total IVF cycle.

Comparison of IVF cost inIran and other countries:

IVF cost in other countries like Turkey, India, Jordan, Europe and USAare much more than IVF cost in Iran. For example, the average IVF cost inTurkey is 3,000-4,000$, India 4,000-5,000$, Europe 4,500-6,000$ and USA10,000-18,000$.

IVF and sex selection by PGD:

Nowadays, the sexuality of infant isimportant for many parents. It’s possible to determine the gender of your childby IVF and sex selection by PGD methods. Preimplantation genetic diagnosis (PGD) is a procedure usedprior to implantation to determine probable genetic disorders and gender ofchild. This technique is done in high-tech laboratories by embryologists.

What is IVF and sex selection by PGD technique?

IVF and PGD is a scientific method used todetermine the gender of your child, as you desire.

Today, development of scientific andlaboratory techniques have facilitate determination of the gender of your childpreimplantation in uterus.

IVF and sex selection by PGD is done inscientific fertility clinics by infertility treatment specialists andembryologists, despite some moral and religious opposition.

IVF and sex selection by PGD has approvedby health ministry and religious centers in Iran and is done frequently.

IVF and sex selection is performed in infertility clinics by PGDtechnique.

In this technique, the ovium (egg)fertilize by the sperm in laboratory environment.

In 3^rdor 5^thdays after fertilizationand cell division, some eggs (embryos) will be selected for genetic test or sexselection.

Here we will explain IVF and sex selectionby PGD technique and the advantage and disadvantage of IVF and sex selection byPGD.

Selected eggs are used to determine genderand probable chromosomal disorders of embryo. This technique is also useful toprevent chromosomal disorders like Down syndrome.

What is the benefit of IVF and sex selection by PGD?

IVF and sex selection by PGD will determinethe gender of your infant with a high success rate (95-99%). IVF and sexselection by PGD will prevent genetic and chromosomal disorder transmissionfrom parents to the child.

In some types of genetic disorders, calledx-related genetic disorders, father or mother or both are transferor of specialgenetic diseases to their child. In these x-related genetic disease, IVF andsex selection by PGD will be useful.

After IVF and sex selection by PGD, parents could decide to give birthto the affected child or not. So they could prevent transmission of thefamilial genetic disease to their next generations.

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IVF and egg donation

IVF procedure

 IVF procedure: 

• Preliminary sonography:

The preliminary sonography is aimed at examining the condition of the uterus for fertilization. Sonography provides information about the condition of ovaries, follicles and the blood flow to ovaries.

• Secondary sonography

On the fifth day of menstruation cycle, another sonography is done. During this sonography the growth of follicles and the thickness of endometrium is examined. The growth of follicles eventually causes ovulation and estrogen production. At this time in order to examine the estrogen of serum, two blood tests will be done. At this stage your doctor might consider applying some technologically advanced techniques such as hysteroscopy which can increase the success rate of IVF significantly according to scientific studies.

• IVF procedure preparation:

Before commencing the IVF procedure, in case you have irregular menstruation cycles your doctor prescribes progesterone.  After 6 days taking progesterone, some doctors might prescribe medications to induce ovulation.

• Proceeding with IVF:

IVF procedure starts with menstruation and on the second day of the period, blood tests and vaginal sonography is done. Sonography is aimed at examining the size of follicles and the blood test is to determine the level of estrogen and estradiol.

·         Testing and stimulating the ovaries:

At this stage, ovaries are stimulated by fertility drugs. Usually these drugs are injectable and you need to have one to four injections a day for a period of seven to 10 days. These drugs help ovary stimulation and controls the growth of oocyte (immature egg).

• Oocyte maturation:

At this stage HCG is injected. The timely injection of HSG is very important. If HCG is injected prematurely egg would not become completely mature and in case of postponing the injection, the egg would become too mature. Normally HCG is injected when the size of follicle has reached to 18 to 20 millimeters and the level of estrogen has reached to over 2000 pg/ml.

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In Vitro Fertilization IVF

In VitroFertilization IVF

In vitro fertilizationIVF is one of the infertility treatments that helps patients tofertilize and reduces the risk of genetic disorders in newborn. DuringIVF mature eggs are extracted from ovaries and manually fertilized by retrievedsperm samples in a laboratory. The fertilized egg or embryo is placed insidethe uterus to increase the chance of pregnancy.

The full cycle of IVFtakes about three to four weeks. The IVF procedure could beperform by using couple’s own egg and sperm or it could involve using eggsand/or sperm from a donor. In some rare cases IVF procedure may require asurrogate uterus for the embryo to be transferred into.

The success rate of IVFdepends on various factors including the age of the couple undergoing theprocedure and the cause of infertility. IVF treatment is time-consuming andexpensive but also is a proper procedure that greatly increases the successrate of pregnancy.

WhyIVF is done?

In vitro fertilizationIVF is a relatively invasive procedure recommended to those whowere unsuccessful with other less invasive treatments such as medication. IVFis considered as a primary treatment for women over age 40. IVF can also bedone when you have some specific health conditions, such as:

• Fallopian tube damage orblockage
• Ovulation disorders
• Endometriosis
• Uterine fibroids
• Previous tubal sterilization orremoval
• Impaired sperm production orfunction
• Unexplained infertility
• Preventing genetic disordersfrom being transmitted to the child
• Fertilitypreservation in cancer treatments or other health conditions

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Best methods of infertility treatment

Best methods of infertility treatment:

Nowadays due to advances in medical sciences and various methods for infertility treatment, the joy of having a child is within the reach of almost anybody. Medical treatments along with assisted reproduction techniques has improved the chance for many men and women with infertility problems to have children. This article gives you useful information about prominent methods of infertility treatment.

The process of infertility treatment:

After various diagnostic tests, different methods of infertility treatment will be applied in accordance with the cause of infertility. After explaining each method and its success rate, doctor provides the couple with different treatment options to choose the one that suits them the most regarding their situation and preferences.

• In vitro fertilization or IVF:

IVF is a prevalent method to treat infertility problems and consisted of a complex series of procedures. During IVF, after stimulating ovaries and ovulation, mature eggs are retrieved from ovaries and fertilized by sperm outside the uterus in a lab. After the conception of embryo in the lab, the embryo is then placed inside the uterus.

This method is usually offered in conditions where sperm can’t reach the egg naturally, such as blocked fallopian tubes, pelvic adhesions, low sperm count or low sperm mobility.

• Intrauterine insemination IUIDuring intrauterine insemination IUI which is a simple and painless procedure to facilitate fertilization, the sperm is placed inside the uterus. For IUI to work(hazf) , the fallopian tubes need to be healthy. In this method the egg is not retrieved from ovaries and the process of ovulation and conception occurs naturally.
• Ovulation stimulation by advanced protocols:
• Ovulation stimulation is helpful for women with irregular ovulation, ovulation disorder or polycystic ovary (PCO) and mostly used to increase the quantity and quality of eggs and boost the chance of fertilization. There are medications that induce the same effect on egg quality and quantity which are known as ovulation induction medicine.
• Micro injection or intracytoplasmic sperm injection ICSI
• Micro injection is an infertility treatment method that a sperm cell is injected directly into the cytoplasm of an egg and cultivate it for a specific period of time in an incubator. After conception and cell division, embryo is made.
• In vitro maturation IVM:
• With IVM, instead of increasing follicle growth in body (metaphase 2), immature eggs are extracted from ovaries using a vaginal sonography. Afterwards, extracted eggs are grown in a laboratory and fertilized before being replaced into the womb.
• Gamete intrafallopian transfer GIFT:

• GIFT method is mostly used in cases of surrogate womb and is similar to IVF in terms of egg retrieving and sperm preparation. Afterwards, the egg along with adequate amount of sperm are placed directly into the fallopian tubes using a laparoscope.

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IVF: success rate

IVF: success rate

What is IVF success rate in Iran?

IVF success rate is an important point you should noticebefore performing IVF.

IVF is an infertility treatment technique for infertilecouples with appropriate and high success rate in Iran compared to othercountries.

What is IVF success rate in Iran compared to other countries?

Fortunately, Iran has a lot of experience in infertilitytreatment science with high IVF success rate compared to countries all over the worldand many patients travel to Iran to treat their infertility problems everyyear.

To evaluate IVF success rate, patients are divided into 2groups: women age less than 35 years old and women age more than 35 years old.

The success rate of IVF in first group (women <35 y/o)is approximately 40 % and the success rate of IVF in second group (women >35 y/o) is 15- 20% on average.

IVF success rate differs in fertility clinics and centersdepend on many factors.

IVF success rate in Iran is equal or more than globalstatistics.

IVF in Iran has affordable costs which make Iran anattractive destination for infertility treatment and medical travelers.

High medical care experiences along with fair priceshighlight Iran as a leading destination for infertility treatment all over theworld.

What affects IVF success rate?

IVF is a technique to treat infertility problems such assperm count, shape or motility problems or insufficient egg production.

IVF is done in special laboratory environment and manyfactors affect IVF success rate which mentioned as below:

Age:

First and most important factor affecting the successrate of IVF is age. The older you get, the lower your chance of successful IVF.In younger people, the chance of access to fresh and young egg and sperm ishigher.

Previous successful pregnancy:

If you had a successful pregnancy previously, the successrate of IVF is more for you compared to others.

The reason of infertility:

Infertility reason affects the IVF success rate. IVFsuccess rate decreases in some infertility causes.

Donated egg quality:

If the woman has an ovulation problem, the solution isusing donated egg.

Young and fresh eggs have more success rate.

Life style:

Some daily habits have a negative impression on IVFsuccess rate including smoking, obesity, high daily stress, etc.

Infertility clinic quality:

Experienced fertility specialists and embryologists alongwith high-tech laboratory equipment will increase IVF success rate to a greatextent.

Iran is an attractive destination for IVF &infertility treatment regarding all positive points we explained.

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IVF : history of IVFinIran

IVF : history of IVFinIran

Thehistory of IVFinIranhasbeen shaped by the interaction between the pioneers of IVF and aninterdisciplinary groupof experts, together with the endorsementand strong support of the Shia jurists.

• 1992 – Birth of the first baby following retrogradeejaculation using intrauterine insemination (IUI) first started in 1989 inAban Hospital by Dr. Jalil Pakravesh (personal communication).
• 1994 – Birth of the first baby resulting from intracytoplasmicsperm injection (ICSI) and the birth of the first baby through eggdonation carried out in Yazd by Dr. Mohmmad-Hossein Amir Arjomand(personal communication).
• 1996/97–Use of ICSI+ percutaneous epididymal spermaspiration (PESA) resulting in the birth of a baby at Shariati Hospital,Tehran, carried out by Dr. Hojat-Allah Saeedi (personal communication).
• 1998–First case of transferring an embryo produced fromtesticular spermatozoon by microinjection carried out by Dr. Akhondi (theauthor).
• 2004–Birth of the first baby bornfollowing pre-implantation genetic diagnosis (PGD) Royan Institute,Tehran, carried out by Dr. Leila Karimian (personal communication).

Indeed, the use ofIVFin a range of contexts such asPGD(more…)(as a preventive measure for diseases with a geneticbasis or for sex selection); sperm, egg and embryo donation; surrogacy;fertility preservation; and animal conservation (freezing of egg, sperm andembryo), are commonplace inIran.

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IVF : Infertility treatment in Iran

IVF : Infertility treatment in Iran

According to the World Health Organization(WHO), infertility is a disease of the reproductive system defined by thefailure to achieve a clinical pregnancy after 12 months of trying.

Infertility affects an estimated 20.4 % ofcouples globally.

The figure will drop to 12.4 percent after twoyears of trying, adding it shows that many infertile couples can have a baby ifthey keep trying.

The couples aged 35 years and above are not recommendedto use the method because any delay in childbearing would aggravate theirinfertility problems(more…).

Iranian couples no longer need to travel abroad forconsultation or treatment forinfertilityas advanced methods of treatmentfor couples who have problems to conceive, are available in the country.

There are 3 million infertile couples in thecountry. Around 3-4% of young Iranian women suffer from recurrentmiscarriages. Infertility rate is about 2.5% and secondary infertility is moreprevalent than primary infertility. When a woman is not able to conceive atall, (due to infertility in either spouse), it is referred to as primaryfertility. Secondary infertility is when a woman is unable to conceive againafter the first successful pregnancy andchildbirth. While causes of secondary infertility vary, the most important riskfactors are advanced reproductive age, weight gain, abdominal surgeries, spermquality and quantity, and smoking.

Microsurgical reconstruction for male infertility, newmethods of maleinfertility treatment(more..)(medication, surgery, andIntracytoplasmicSperm Injection (ICSI)(more…)), the role ofcomplementary therapies and medicines to improve fertility, and new imagingtechniques for assessment of infertility problems in both genders, are amongthe main important topics that will be discussed.

At present, there are 80 infertility centersacross the country and 20 more will be launched by the end of the current year.

Additionally, 35 state-run universities of medicalsciences have equipped with new laboratory equipment and devices foridentification and treatment of infertility problems.

IVF is never the first stepin the treatment of infertility. Instead, it’s reserved for cases in which other methods such as fertility drugs, surgery, and artificialinsemination haven’t worked.

On average, an IVF cycle costs $2,300-$2,900in the country, while the majority of women have per-cycle success rates of20-35%, which means they may need multiple tries to get pregnant.

IVF may be an option if one of the spouses or both hasbeen diagnosed with problems like endometriosis, low sperm count, problems withovulation, antibody problems that harm sperms or eggs, and unexplainedfertility problems.

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IVF: side effects Typical side effects include: •Passing a small amount of clear or bloody fluid shortly after the procedure — due to the swabbing of the cervix before the embryo transfer •Breast tenderness due to high estrogen levels •Mild bloating •Mild cramping •Constipation If you develop m

IVF: side effects

Typical side effects include:

• Passing a smallamount of clear or bloody fluid shortly after the procedure — due to theswabbing of the cervix before the embryo transfer
• Breasttenderness due to high estrogen levels
• Mild bloating
• Mild cramping
• Constipation

If you develop moderate or severe painafter the embryo transfer, contact your doctor. He or she will evaluate you for complications such as infection,twisting of an ovary (ovarian torsion) and severe ovarian hyperstimulationsyndrome.

About 12 days to two weeks after egg retrieval,your doctor will test a sample of your blood to detect whether you’re pregnant.

• If you’re pregnant, your doctor will refer you to anobstetrician or another pregnancy specialist for prenatal care.
• If you’re not pregnant, you’ll stop taking progesterone andlikely get your period within a week. If you don’t get your period or youhave unusual bleeding, contact your doctor. If you’re interested inattempting another cycle of in vitro fertilization (IVF), your doctor might suggest steps you cantake to improve your chances of getting pregnant through IVF.

The chances of giving birth to a healthybaby after using IVF depend on various factors, including:

• Maternal age. The younger you are, the more likelyyou are to get pregnant and give birth to a healthy baby using your owneggs during IVF. Women age 41 and older are often counseled to considerusing donor eggs during IVF to increase the chances of success.
• Embryo status. Transfer of embryos that are moredeveloped is associated with higher pregnancy rates compared with lessdeveloped embryos (day two or three). However, not all embryos survive thedevelopment process. Talk with your doctor or another care provider aboutyour specific situation.
• Reproductive history. Women who’ve previously given birthare more likely to be able to get pregnant using IVF than are women who’venever given birth. Successrates are lower forwomen who’ve previously used IVF multiple times but didn’t get pregnant.
• Cause of infertility. Having a normal supply of eggsincreases your chances of being able to get pregnant using IVF. Women whohave severe endometriosis are less likely to be able to get pregnant usingIVF than are women who have unexplained infertility(more…).
• Lifestyle factors. Women who smoke typically have fewereggs retrieved during IVF and may miscarry more often. Smoking can lower awoman’s chance of success using IVF by 50 percent. Obesity can decreaseyour chances of getting pregnant and having a baby. Use of alcohol,recreational drugs, excessive caffeine, and certain medications also canbe harmful.

Talk with our doctors about any factorsthat apply to you and how they may affect your chances of a successfulpregnancy.

 

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Typical side effects include:

• Passing a smallamount of clear or bloody fluid shortly after the procedure — due to theswabbing of the cervix before the embryo transfer
• Breasttenderness due to high estrogen levels
• Mild bloating
• Mild cramping
• Constipation

If you develop moderate or severe painafter the embryo transfer, contact your doctor. He or she will evaluate you for complications such as infection,twisting of an ovary (ovarian torsion) and severe ovarian hyperstimulationsyndrome.

About 12 days to two weeks after egg retrieval,your doctor will test a sample of your blood to detect whether you’re pregnant.

• If you’re pregnant,your doctor will refer you to anobstetrician or another pregnancy specialist for prenatal care.
• If you’re not pregnant,you’ll stop taking progesterone andlikely get your period within a week. If you don’t get your period or youhave unusual bleeding, contact your doctor. If you’re interested inattempting another cycle of in vitro fertilization (IVF), your doctor might suggest steps you cantake to improve your chances of getting pregnant through IVF.

The chances of giving birth to a healthybaby after using IVF depend on various factors, including:

• Maternal age.The younger you are, the more likelyyou are to get pregnant and give birth to a healthy baby using your owneggs during IVF. Women age 41 and older are often counseled to considerusing donor eggs during IVF to increase the chances of success.
• Embryo status.Transfer of embryos that are moredeveloped is associated with higher pregnancy rates compared with lessdeveloped embryos (day two or three). However, not all embryos survive thedevelopment process. Talk with your doctor or another care provider aboutyour specific situation.
• Reproductive history.Women who’ve previously given birthare more likely to be able to get pregnant using IVF than are women who’venever given birth. Successrates are lower forwomen who’ve previously used IVF multiple times but didn’t get pregnant.
• Cause of infertility.Having a normal supply of eggsincreases your chances of being able to get pregnant using IVF. Women whohave severe endometriosis are less likely to be able to get pregnant usingIVF than are women who have unexplainedinfertility(more…).
• Lifestyle factors.Women who smoke typically have fewereggs retrieved during IVF and may miscarry more often. Smoking can lower awoman’s chance of success using IVF by 50 percent. Obesity can decreaseyour chances of getting pregnant and having a baby. Use of alcohol,recreational drugs, excessive caffeine, and certain medications also canbe harmful.

Talk with our doctors about any factorsthat apply to you and how they may affect your chances of a successfulpregnancy.

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IVF: Ovulation induction

IVF:Ovulation induction

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If you’re using your own eggsduring IVF, at the start of a cycle you’ll begin treatment with synthetichormones to stimulate your ovaries to produce multiple eggs — rather than thesingle egg that normally develops each month. Multiple eggs are needed becausesome eggs won’t fertilize or develop normally after fertilization.

You may need several different medications,such as:

• Medications for ovarian stimulation.To stimulate your ovaries, you might receivean injectable medication containing a follicle-stimulating hormone (FSH),a luteinizing hormone (LH) or a combination of both. These medicationsstimulate more than one egg to develop at a time.
• Medications for oocyte maturation.When the follicles are ready for egg retrieval— generally after eight to 14 days — you will take human chorionicgonadotropin (HCG) or other medications to help the eggs mature.
• Medications to prevent prematureovulation.These medications prevent your bodyfrom releasing the developing eggs too soon.
• Medications toprepare the lining of your uterus.On theday of egg retrieval or at the time of embryo transfer, your doctor might recommend that you begin taking progesterone supplements tomake the lining of your uterus more receptive to implantation.

Your doctor will work with you todetermine which medications to use and when to use them.

Typically, you’ll need one to twoweeks of ovarian stimulation before your eggs are ready for retrieval. Todetermine when the eggs are ready for collection, your doctor will likelyperform:

• A vaginal ultrasound,an imaging exam of your ovaries to monitor thedevelopment of follicles — fluid-filled ovarian sacs where eggs mature
• Blood tests,to measure your response to ovarianstimulation medications — estrogen levels typically increase as folliclesdevelop and progesterone levels remain low until after ovulation

Sometimes IVF cycles need to be canceled beforeegg retrieval for one of these reasons:

• Inadequate number of follicles developing
• Premature ovulation
• Too many follicles developing, creating arisk of ovarian hyperstimulation syndrome
• Other medicalissues

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